Advantages ofSingle Domain Antibody

• High stability to function and exist within extreme conditions (high temperatures and pH).
• Can recognize novel epitopes that are normally not recognized by conventional antibodies.
• Their small molecular size helps with rapid tissue penetration and labeling applications, including crossing the blood-brain barrier.
• Improved bioavailability for pharmaceutical applications.
• Cheaper alternative for large-scale production.
• Increased potential in downstream antibody engineering (bi-specific antibody, humanization).
• Can be expressed in both eukaryotic and prokaryotic systems.

Engineered sdAb

Singh Biotechnology using our proprietary technology have successfully bio-engineered multiple sdAb to specifically target and inhibit :

• STAT3 (Signal Transducer and Activator of Transcription 3)
• KRAS (Kirsten Rat Sarcoma)
• TNF-α (Tumor Necrosis Factor Alpha)